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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vav1M5Btlr
mutation 5, Bruce Beutler
MGI:6285528
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vav1M5Btlr/Vav1M5Btlr C57BL/6J-Vav1M5Btlr MGI:6285535


Genotype
MGI:6285535
hm1
Allelic
Composition		 Vav1M5Btlr/Vav1M5Btlr
Genetic
Background		 C57BL/6J-Vav1M5Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vav1M5Btlr mutation (0 available); any Vav1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased CD8-positive, alpha-beta T cell number ( J:272529 )
• reduced CD8+ T cell frequencies in the peripheral blood

hematopoietic system
decreased CD8-positive, alpha-beta T cell number ( J:272529 )
• reduced CD8+ T cell frequencies in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory