All Phenotypes Dock8<M3Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dock8^M3Btlr
mutation 3, Bruce Beutler
MGI:6285541

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dock8^M3Btlr/Dock8^M3Btlr	C57BL/6J-Dock8^M3Btlr	MGI:6285543

Allelic Composition	Dock8^M3Btlr/Dock8^M3Btlr
Genetic Background	C57BL/6J-Dock8^M3Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8^M3Btlr mutation (0 available); any Dock8 mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgG level ( J:272531 )

• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

impaired humoral immune response ( J:272531 )

• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

hematopoietic system

decreased IgG level ( J:272531 )

• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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