All Phenotypes Dock8<M3Btlr> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dock8^M3Btlr
mutation 3, Bruce Beutler
MGI:6285541

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dock8^M3Btlr/Dock8^M3Btlr	C57BL/6J-Dock8^M3Btlr	MGI:6285543

Allelic Composition	Dock8^M3Btlr/Dock8^M3Btlr
Genetic Background	C57BL/6J-Dock8^M3Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8^M3Btlr mutation (0 available); any Dock8 mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgG level ( J:272531 )

• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

impaired humoral immune response ( J:272531 )

• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

hematopoietic system

decreased IgG level ( J:272531 )

• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24