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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgamm2Btlr
mutation 2, Bruce Beutler
MGI:6285545
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgamm2Btlr/Itgamm2Btlr C57BL/6J-Itgamm2Btlr MGI:6285547


Genotype
MGI:6285547
hm1
Allelic
Composition		 Itgamm2Btlr/Itgamm2Btlr
Genetic
Background		 C57BL/6J-Itgamm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgamm2Btlr mutation (0 available); any Itgam mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD11b-high dendritic cell number ( J:272532 )
• reduced frequency of CD11b+dendritic cells (DCs) gated in CD11c+cells in the peripheral blood

immune system
decreased CD11b-high dendritic cell number ( J:272532 )
• reduced frequency of CD11b+dendritic cells (DCs) gated in CD11c+cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory