About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgamm3Btlr
mutation 3, Bruce Beutler
MGI:6285549
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgamm3Btlr/Itgamm3Btlr C57BL/6J-Itgamm3Btlr MGI:6285555


Genotype
MGI:6285555
hm1
Allelic
Composition		 Itgamm3Btlr/Itgamm3Btlr
Genetic
Background		 C57BL/6J-Itgamm3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgamm3Btlr mutation (0 available); any Itgam mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD11b-high dendritic cell number ( J:272533 )
• reduced frequency of CD11b+dendritic cells (DCs) gated in CD11c+cells in the peripheral blood

immune system
decreased CD11b-high dendritic cell number ( J:272533 )
• reduced frequency of CD11b+dendritic cells (DCs) gated in CD11c+cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory