Phenotypes associated with this allele

• Allele Symbol: Stk4^m5Btlr
• Allele Name: mutation 5, Bruce Beutler
• Allele ID: MGI:6285636
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stk4^m5Btlr/Stk4^m5Btlr	C57BL/6J-Stk4^m5Btlr	MGI:6285638

Genotype
MGI:6285638

hm1

• Allelic Composition: Stk4^m5Btlr/Stk4^m5Btlr
• Genetic Background: C57BL/6J-Stk4^m5Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal T cell differentiation ( J:272743 )

• increased CD44 expression on peripheral blood T cells

abnormal CD4-positive T cell differentiation ( J:272743 )

• increased CD44 expression on CD4+ T cells

increased central memory CD4-positive, alpha-beta T cell number ( J:272743 )

• increased frequencies of central memory CD4 T cells in CD4 T cells in the peripheral blood

decreased CD4-positive, alpha-beta T cell number ( J:272743 )

• reduced frequencies of naive CD4 T cells in CD4 T cells in the peripheral blood

hematopoietic system

abnormal T cell differentiation ( J:272743 )

• increased CD44 expression on peripheral blood T cells

abnormal CD4-positive T cell differentiation ( J:272743 )

• increased CD44 expression on CD4+ T cells

increased central memory CD4-positive, alpha-beta T cell number ( J:272743 )

• increased frequencies of central memory CD4 T cells in CD4 T cells in the peripheral blood

decreased CD4-positive, alpha-beta T cell number ( J:272743 )

• reduced frequencies of naive CD4 T cells in CD4 T cells in the peripheral blood