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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		PtprcM10Btlr
mutation 10, Bruce Beutler
MGI:6285772
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		PtprcM10Btlr/PtprcM10Btlr C57BL/6J-PtprcM10Btlr MGI:6285774


Genotype
MGI:6285774
hm1
Allelic
Composition		 PtprcM10Btlr/PtprcM10Btlr
Genetic
Background		 C57BL/6J-PtprcM10Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
PtprcM10Btlr mutation (0 available); any Ptprc mutation (189 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B-1b cell number ( J:272777 )
• reduced frequencies of B1b cells in B1 cells in the peripheral blood
decreased IgE level ( J:272777 )
• reduced circulating levels of total IgE

hematopoietic system
decreased B-1b cell number ( J:272777 )
• reduced frequencies of B1b cells in B1 cells in the peripheral blood
decreased IgE level ( J:272777 )
• reduced circulating levels of total IgE




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory