All Phenotypes Mlkl<M4Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mlkl^M4Btlr
mutation 4, Bruce Beutler
MGI:6285950

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mlkl^M4Btlr/Mlkl^M4Btlr	C57BL/6J-Mlkl^M4Btlr	MGI:6285955

Allelic Composition	Mlkl^M4Btlr/Mlkl^M4Btlr
Genetic Background	C57BL/6J-Mlkl^M4Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlkl^M4Btlr mutation (0 available); any Mlkl mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

decreased apoptosis ( J:272831 )

• resistance to lipopolysaccharide (LPS)-induced necroptosis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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