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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ppp3cbM6Btlr
mutation 6, Bruce Beutler
MGI:6286032
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ppp3cbM6Btlr/Ppp3cbM6Btlr C57BL/6J-Ppp3cbM6Btlr MGI:6286034


Genotype
MGI:6286034
hm1
Allelic
Composition
Ppp3cbM6Btlr/Ppp3cbM6Btlr
Genetic
Background
C57BL/6J-Ppp3cbM6Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp3cbM6Btlr mutation (0 available); any Ppp3cb mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• increase in the B to T cell ratio in the peripheral blood
• reduced frequencies of T cells in the peripheral blood
• reduced frequencies of CD4+ T cells in the peripheral blood
• reduced frequencies of CD8+ T cells in the peripheral blood

hematopoietic system
• increase in the B to T cell ratio in the peripheral blood
• reduced frequencies of T cells in the peripheral blood
• reduced frequencies of CD4+ T cells in the peripheral blood
• reduced frequencies of CD8+ T cells in the peripheral blood





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory