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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zap70m8Btlr
mutation 8, Bruce Beutler
MGI:6286299
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zap70m8Btlr/Zap70m8Btlr C57BL/6J-Zap70m8Btlr MGI:6286303


Genotype
MGI:6286303
hm1
Allelic
Composition		 Zap70m8Btlr/Zap70m8Btlr
Genetic
Background		 C57BL/6J-Zap70m8Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zap70m8Btlr mutation (0 available); any Zap70 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased central memory CD8 positive, alpha-beta T cell number ( J:272864 )
• increased frequencies of central memory CD8 T cells in CD8 T cells in the peripheral blood
decreased CD8-positive, naive alpha-beta T cell number ( J:272864 )
• reduced frequencies of naive CD8 T cells in CD8 T cells in the peripheral blood

hematopoietic system
increased central memory CD8 positive, alpha-beta T cell number ( J:272864 )
• increased frequencies of central memory CD8 T cells in CD8 T cells in the peripheral blood
decreased CD8-positive, naive alpha-beta T cell number ( J:272864 )
• reduced frequencies of naive CD8 T cells in CD8 T cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory