Phenotypes associated with this allele

• Allele Symbol: U2af1^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:6294123
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	U2af1^em1(IMPC)J/U2af1^em1(IMPC)J	C57BL/6NJ-U2af1^em1(IMPC)J/Mmjax	MGI:7267129
ht2	U2af1^em1(IMPC)J/U2af1^+	C57BL/6NJ-U2af1^em1(IMPC)J/Mmjax	MGI:7317089

Genotype
MGI:7267129

hm1

• Allelic Composition: U2af1^em1(IMPC)J/U2af1^em1(IMPC)J
• Genetic Background: C57BL/6NJ-U2af1^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for U2af1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:7317089

ht2

• Allelic Composition: U2af1^em1(IMPC)J/U2af1⁺
• Genetic Background: C57BL/6NJ-U2af1^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for U2af1

behavior/neurological

increased grip strength ( J:211773 )

♀

IMPC - JAX

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

integument

abnormal coat/hair pigmentation ( J:211773 )

IMPC - JAX

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

IMPC - JAX

vision/eye

irregularly shaped pupil ( J:211773 )

IMPC - JAX

cornea opacity ( J:211773 )

IMPC - JAX

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - JAX