Phenotypes associated with this allele

• Allele Symbol: Fancd2^{em1(IMPC)Hmgu}
• Allele Name: endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6302758
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fancd2^em1(IMPC)Hmgu/Fancd2^em1(IMPC)Hmgu	C57BL/6NCrl-Fancd2^em1(IMPC)Hmgu/Ieg	MGI:7414889
ht2	Fancd2^em1(IMPC)Hmgu/Fancd2^+	C57BL/6NCrl-Fancd2^em1(IMPC)Hmgu/Ieg	MGI:7414888

Genotype
MGI:7414889

hm1

• Allelic Composition: Fancd2^{em1(IMPC)Hmgu}/Fancd2^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6NCrl-Fancd2^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Fancd2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:7414888

ht2

• Allelic Composition: Fancd2^{em1(IMPC)Hmgu}/Fancd2⁺
• Genetic Background: C57BL/6NCrl-Fancd2^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Fancd2

behavior/neurological

decreased locomotor activity ( J:211773 )

♀

IMPC - HMGU

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HMGU

homeostasis/metabolism

increased circulating iron level ( J:211773 )

♀

IMPC - HMGU

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HMGU