Phenotypes associated with this allele

• Allele Symbol: Mllt10^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6313349
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mllt10^em1(IMPC)Mbp/Mllt10^em1(IMPC)Mbp	C57BL/6N-Mllt10^em1(IMPC)Mbp/MbpMmucd	MGI:6480509
ht2	Mllt10^em1(IMPC)Mbp/Mllt10^+	C57BL/6N-Mllt10^em1(IMPC)Mbp/MbpMmucd	MGI:6492956

Genotype
MGI:6480509

hm1

• Allelic Composition: Mllt10^em1(IMPC)Mbp/Mllt10^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Mllt10^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Mllt10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - UCD

abnormal facial morphology ( J:211773 )

IMPC - UCD

facial cleft ( J:211773 )

♀

IMPC - UCD

embryo

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - UCD

facial cleft ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

Genotype
MGI:6492956

ht2

• Allelic Composition: Mllt10^em1(IMPC)Mbp/Mllt10⁺
• Genetic Background: C57BL/6N-Mllt10^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Mllt10

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

digestive/alimentary system

abnormal cecum morphology ( J:211773 )

♂

IMPC - UCD

enlarged cecum ( J:211773 )

♂

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

decreased body length ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

♀

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

limbs/digits/tail

abnormal caudal vertebrae morphology ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

skeleton

abnormal caudal vertebrae morphology ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD