Phenotypes associated with this allele

• Allele Symbol: Mfsd1^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:6313359
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mfsd1^em1(IMPC)Tcp/Mfsd1^em1(IMPC)Tcp	C57BL/6N-Mfsd1^em1(IMPC)Tcp/Tcp	MGI:6480505
ht2	Mfsd1^em1(IMPC)Tcp/Mfsd1^+	C57BL/6N-Mfsd1^em1(IMPC)Tcp/Tcp	MGI:6492953

Genotype
MGI:6480505

hm1

• Allelic Composition: Mfsd1^em1(IMPC)Tcp/Mfsd1^em1(IMPC)Tcp
• Genetic Background: C57BL/6N-Mfsd1^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Mfsd1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

small testis ( J:211773 )

♂

IMPC - TCP

growth/size/body

enlarged spleen ( J:211773 )

IMPC - TCP

hematopoietic system

enlarged spleen ( J:211773 )

IMPC - TCP

increased red blood cell distribution width ( J:211773 )

♂

IMPC - TCP

increased neutrophil cell number ( J:211773 )

♂

IMPC - TCP

thrombocytopenia ( J:211773 )

♂

IMPC - TCP

increased mean platelet volume ( J:211773 )

♂

IMPC - TCP

decreased leukocyte cell number ( J:211773 )

♂

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - TCP

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - TCP

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - TCP

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - TCP

immune system

enlarged spleen ( J:211773 )

IMPC - TCP

increased neutrophil cell number ( J:211773 )

♂

IMPC - TCP

decreased leukocyte cell number ( J:211773 )

♂

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

reproductive system

small testis ( J:211773 )

♂

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

♀

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - TCP

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - TCP

Genotype
MGI:6492953

ht2

• Allelic Composition: Mfsd1^em1(IMPC)Tcp/Mfsd1⁺
• Genetic Background: C57BL/6N-Mfsd1^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Mfsd1

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP

vision/eye

anophthalmia ( J:211773 )

♂

IMPC - TCP