Phenotypes associated with this allele

• Allele Symbol: Atp13a3^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:6314147
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atp13a3^em1(IMPC)J/Atp13a3^em1(IMPC)J	C57BL/6NJ-Atp13a3^em1(IMPC)J/Mmjax	MGI:7316957

Genotype
MGI:7316957

hm1

• Allelic Composition: Atp13a3^em1(IMPC)J/Atp13a3^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Atp13a3^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Atp13a3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - JAX

increased anxiety-related response ( J:211773 )

IMPC - JAX

increased startle reflex ( J:211773 )

♂

IMPC - JAX

decreased locomotor activity ( J:211773 )

IMPC - JAX

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - JAX

increased heart weight ( J:211773 )

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

IMPC - JAX

hematopoietic system

increased erythrocyte cell number ( J:211773 )

IMPC - JAX

increased hematocrit ( J:211773 )

IMPC - JAX

decreased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - JAX

decreased mean corpuscular volume ( J:211773 )

IMPC - JAX

thrombocytopenia ( J:211773 )

IMPC - JAX

increased leukocyte cell number ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased blood urea nitrogen level ( J:211773 )

IMPC - JAX

increased circulating bilirubin level ( J:211773 )

IMPC - JAX

decreased circulating glucose level ( J:211773 )

IMPC - JAX

decreased fasting circulating glucose level ( J:211773 )

IMPC - JAX

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - JAX

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - JAX

increased circulating aspartate transaminase level ( J:211773 )

IMPC - JAX

decreased circulating serum albumin level ( J:211773 )

IMPC - JAX

decreased circulating total protein level ( J:211773 )

IMPC - JAX

improved glucose tolerance ( J:211773 )

IMPC - JAX

abnormal cholesterol homeostasis ( J:211773 )

♀

IMPC - JAX

decreased circulating cholesterol level ( J:211773 )

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - JAX

immune system

increased leukocyte cell number ( J:211773 )

IMPC - JAX

integument

abnormal skin coloration ( J:211773 )

♀

IMPC - JAX

reproductive system

male infertility ( J:211773 )

♂

IMPC - JAX

skeleton

increased bone mineral content ( J:211773 )

♂

IMPC - JAX

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - JAX