Analysis Tools
skeleton
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• osteoblasts in calvarias are more active
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• calvarial area and density are increased, mean bone volume and mean bone thickness are increased, and mean bone separation is decreased
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• mean bone thickness is increased in calvaria
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• many bones at P3 are more densely stained with Alizarin Red indicating increased bone density
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• bone volume to tissue volume is increased in calvaria
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• calvarial and femoral bones are developed to a greater extent than in wild-type mice at P3
• osteoblast surface per bone surface is increased in P3 calvaria but osteoblast number per bone perimeter is not altered indicting more active osteoblasts and increased bone development
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• primary osteoblasts show increased differentiation in culture upon induction with BMP-2
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craniofacial
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• calvarial area and density are increased, mean bone volume and mean bone thickness are increased, and mean bone separation is decreased
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• mean bone thickness is increased in calvaria
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cellular
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• primary osteoblasts show increased differentiation in culture upon induction with BMP-2
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• osteoblasts in calvarias are more active
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