Phenotypes associated with this allele

• Allele Symbol: Ndufa10^{tm1e.1(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1e.1, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6317360
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ndufa10^tm1e.1(EUCOMM)Hmgu/Ndufa10^tm1e.1(EUCOMM)Hmgu	C57BL/6N-Ndufa10^tm1e.1(EUCOMM)Hmgu/Ieg	MGI:6408525
ht2	Ndufa10^tm1e.1(EUCOMM)Hmgu/Ndufa10^+	C57BL/6N-Ndufa10^tm1e.1(EUCOMM)Hmgu/Ieg	MGI:6408524

Genotype
MGI:6408525

hm1

• Allelic Composition: Ndufa10^{tm1e.1(EUCOMM)Hmgu}/Ndufa10^{tm1e.1(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ndufa10^{tm1e.1(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0520_4_F03

Data Sources

IMPC Data for Ndufa10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6408524

ht2

• Allelic Composition: Ndufa10^{tm1e.1(EUCOMM)Hmgu}/Ndufa10⁺
• Genetic Background: C57BL/6N-Ndufa10^{tm1e.1(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0520_4_F03

Data Sources

IMPC Data for Ndufa10

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HMGU

behavior/neurological

abnormal gait ( J:211773 )

IMPC - HMGU

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - HMGU

decreased bone mineral density ( J:211773 )

IMPC - HMGU