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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ddx3yem2Osb
endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI:6323445
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Ddx3xem1Osb/Y
X/Ddx3yem2Osb 		involves: C57BL/6NJcl * DBA/2NJcl MGI:6379312
ot2
 		X/Ddx3yem2Osb involves: C57BL/6NJcl * DBA/2NJcl MGI:6379310


Genotype
MGI:6379312
cx1
Allelic
Composition		 Ddx3xem1Osb/Y
X/Ddx3yem2Osb
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddx3xem1Osb mutation (0 available); any Ddx3x mutation (8 available)
Ddx3yem2Osb mutation (2 available); any Ddx3y mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality prior to tooth bud stage ( J:274336 )
• no males are obtained; only 2.9% male embryos are seen at E10.5, much lower than the expected 25% indicating embryonic lethality before E10.5

growth/size/body
decreased embryo size ( J:274336 )
• the one E10.5 embryo obtained is smaller than wild-type embryos

embryo
decreased embryo size ( J:274336 )
• the one E10.5 embryo obtained is smaller than wild-type embryos




Genotype
MGI:6379310
ot2
Allelic
Composition		 X/Ddx3yem2Osb
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddx3yem2Osb mutation (2 available); any Ddx3y mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:274336 )
N
• males show no abnormality in spermatogenesis at 15 weeks of age, have normal spermatozoa and sire offspring, indicating normal fertility




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory