Phenotypes associated with this allele

• Allele Symbol: Tg(CAG-Ptafr)1Tksh
• Allele Name: transgene insertion 1, Takao Shimizu
• Allele ID: MGI:6324050
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CAG-Ptafr)1Tksh/0	B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc	MGI:6324051

Genotype
MGI:6324051

tg1

• Allelic Composition: Tg(CAG-Ptafr)1Tksh/0
• Genetic Background: B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal offspring retrieval ( J:38639 )

growth/size/body

abnormal ear pigmentation ( J:38639 )

decreased body weight ( J:38639 )

craniofacial

abnormal ear pigmentation ( J:38639 )

hearing/vestibular/ear

abnormal ear pigmentation ( J:38639 )

hematopoietic system

increased mast cell number ( J:38639 )

immune system

increased mast cell number ( J:38639 )

increased susceptibility to endotoxin shock ( J:38639 )

integument

thick epidermis stratum basale ( J:38639 )

abnormal skin pigmentation ( J:38639 )

abnormal ear pigmentation ( J:38639 )

abnormal tail pigmentation ( J:38639 )

increased cutaneous melanoma incidence ( J:38639 )

limbs/digits/tail

abnormal tail pigmentation ( J:38639 )

neoplasm

increased cutaneous melanoma incidence ( J:38639 )

pigmentation

abnormal skin pigmentation ( J:38639 )

abnormal ear pigmentation ( J:38639 )

abnormal tail pigmentation ( J:38639 )

abnormal melanosome morphology ( J:38639 )

respiratory system

thick lung-associated mesenchyme ( J:38639 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
skin melanoma		DOID:8923	OMIM:608035 OMIM:612263	J:38639