Phenotypes associated with this allele

• Allele Symbol: Fst^{em1(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:6333014
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fst^em1(IMPC)Wtsi/Fst^em1(IMPC)Wtsi	C57BL/6NCrl-Fst^em1(IMPC)Wtsi/Wtsi	MGI:7629002
ht2	Fst^em1(IMPC)Wtsi/Fst^+	C57BL/6NCrl-Fst^em1(IMPC)Wtsi/Wtsi	MGI:7629001

Genotype
MGI:7629002

hm1

• Allelic Composition: Fst^{em1(IMPC)Wtsi}/Fst^{em1(IMPC)Wtsi}
• Genetic Background: C57BL/6NCrl-Fst^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Fst

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:7629001

ht2

• Allelic Composition: Fst^{em1(IMPC)Wtsi}/Fst⁺
• Genetic Background: C57BL/6NCrl-Fst^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Fst

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HMGU

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - HMGU

skeleton

decreased bone mineral density ( J:211773 )

♂

IMPC - HMGU

vision/eye

abnormal vitreous body morphology ( J:211773 )

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

IMPC - HMGU