Phenotypes associated with this allele

• Allele Symbol: Atg4b^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6336219
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atg4b^tm1b(EUCOMM)Hmgu/Atg4b^tm1b(EUCOMM)Hmgu	C57BL/6N-Atg4b^tm1b(EUCOMM)Hmgu/H	MGI:6408252

Genotype
MGI:6408252

hm1

• Allelic Composition: Atg4b^{tm1b(EUCOMM)Hmgu}/Atg4b^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Atg4b^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0752_1_B03

Data Sources

IMPC Data for Atg4b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

limb grasping ( J:211773 )

♀

IMPC - HAR

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

decreased lean body mass ( J:211773 )

♂

IMPC - HAR

hematopoietic system

increased red blood cell distribution width ( J:211773 )

IMPC - HAR

thrombocytopenia ( J:211773 )

♂

IMPC - HAR

increased mean platelet volume ( J:211773 )

IMPC - HAR

increased leukocyte cell number ( J:211773 )

♀

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - HAR

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

decreased circulating total protein level ( J:211773 )

IMPC - HAR

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - HAR

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

short tibia ( J:211773 )

♀

IMPC - HAR

vision/eye

cataract ( J:211773 )

♀

IMPC - HAR

abnormal retina morphology ( J:211773 )

IMPC - HAR