Phenotypes associated with this allele

• Allele Symbol: Sox14^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6341893
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sox14^em1(IMPC)Ccpcz/Sox14^em1(IMPC)Ccpcz	C57BL/6N-Sox14^em1(IMPC)Ccpcz/Ccpcz	MGI:6731444
ht2	Sox14^em1(IMPC)Ccpcz/Sox14^+	C57BL/6N-Sox14^em1(IMPC)Ccpcz/Ccpcz	MGI:6731443

Genotype
MGI:6731444

hm1

• Allelic Composition: Sox14^{em1(IMPC)Ccpcz}/Sox14^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6N-Sox14^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Sox14

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - CCP-IMG

increased aggression ( J:211773 )

♂

IMPC - CCP-IMG

decreased anxiety-related response ( J:211773 )

♂

IMPC - CCP-IMG

decreased thigmotaxis ( J:211773 )

IMPC - CCP-IMG

increased freezing behavior ( J:211773 )

♀

IMPC - CCP-IMG

decreased startle reflex ( J:211773 )

IMPC - CCP-IMG

limb grasping ( J:211773 )

♂

IMPC - CCP-IMG

increased grip strength ( J:211773 )

IMPC - CCP-IMG

trunk curl ( J:211773 )

♂

IMPC - CCP-IMG

abnormal gait ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♀

IMPC - CCP-IMG

hyperactivity ( J:211773 )

IMPC - CCP-IMG

abnormal vocalization ( J:211773 )

♂

IMPC - CCP-IMG

craniofacial

abnormal snout morphology ( J:211773 )

♀

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

abnormal snout morphology ( J:211773 )

♀

IMPC - CCP-IMG

decreased body weight ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

homeostasis/metabolism

decreased respiratory quotient ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal lymph node morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

♀

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - CCP-IMG

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - CCP-IMG

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

♂

IMPC - CCP-IMG

male infertility ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

increased airway resistance ( J:211773 )

♂

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - CCP-IMG

microphthalmia ( J:211773 )

♀

IMPC - CCP-IMG

Genotype
MGI:6731443

ht2

• Allelic Composition: Sox14^{em1(IMPC)Ccpcz}/Sox14⁺
• Genetic Background: C57BL/6N-Sox14^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Sox14

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

small heart ( J:211773 )

♀

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

nervous system

increased prepulse inhibition ( J:211773 )

IMPC - CCP-IMG

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - CCP-IMG

microphthalmia ( J:211773 )

♂

IMPC - CCP-IMG