Phenotypes associated with this allele

• Allele Symbol: Asb7^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6341901
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Asb7^em1(IMPC)Ccpcz/Asb7^em1(IMPC)Ccpcz	C57BL/6N-Asb7^em1(IMPC)Ccpcz/Ccpcz	MGI:6492711

Genotype
MGI:6492711

hm1

• Allelic Composition: Asb7^{em1(IMPC)Ccpcz}/Asb7^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6N-Asb7^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Asb7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - CCP-IMG

decreased grip strength ( J:211773 )

♀

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♂

IMPC - CCP-IMG

cardiovascular system

dilated aorta ( J:211773 )

♂

IMPC - CCP-IMG

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

increased cardiac muscle contractility ( J:211773 )

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

increased kidney weight ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

decreased leukocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased CD8-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - CCP-IMG

immune system

decreased leukocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased CD8-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - CCP-IMG

muscle

increased cardiac muscle contractility ( J:211773 )

IMPC - CCP-IMG

renal/urinary system

increased kidney weight ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged uterus ( J:211773 )

♀

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - CCP-IMG

anophthalmia ( J:211773 )

♂

IMPC - CCP-IMG