Phenotypes associated with this allele

• Allele Symbol: Lamtor4^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6341931
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lamtor4^em1(IMPC)Ccpcz/Lamtor4^em1(IMPC)Ccpcz	C57BL/6N-Lamtor4^em1(IMPC)Ccpcz/Ccpcz	MGI:6408476
ht2	Lamtor4^em1(IMPC)Ccpcz/Lamtor4^+	C57BL/6N-Lamtor4^em1(IMPC)Ccpcz/Ccpcz	MGI:6408475

Genotype
MGI:6408476

hm1

• Allelic Composition: Lamtor4^{em1(IMPC)Ccpcz}/Lamtor4^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6N-Lamtor4^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Lamtor4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - CCP-IMG

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:6408475

ht2

• Allelic Composition: Lamtor4^{em1(IMPC)Ccpcz}/Lamtor4⁺
• Genetic Background: C57BL/6N-Lamtor4^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Lamtor4

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - CCP-IMG

decreased thigmotaxis ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

IMPC - CCP-IMG

hyperactivity ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thyroid gland morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged thyroid gland ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

decreased mean platelet volume ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal rib morphology ( J:211773 )

IMPC - CCP-IMG