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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Amelxem1(IMPC)Ccpcz
endonuclease-mediated mutation 1, Institute of Molecular Genetics
MGI:6341952
Summary 3 genotypes


Genotype
MGI:6731245
hm1
Allelic
Composition		 Amelxem1(IMPC)Ccpcz/Amelxem1(IMPC)Ccpcz
Genetic
Background		 C57BL/6N-Amelxem1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelxem1(IMPC)Ccpcz mutation (1 available); any Amelx mutation (26 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG
absent teeth ( J:211773 )
IMPC - CCP-IMG

digestive/alimentary system
enlarged stomach ( J:211773 )
IMPC - CCP-IMG

endocrine/exocrine glands
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

growth/size/body
abnormal tooth morphology ( J:211773 )
IMPC - CCP-IMG
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG
absent teeth ( J:211773 )
IMPC - CCP-IMG
decreased body weight ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

respiratory system

skeleton
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG
absent teeth ( J:211773 )
IMPC - CCP-IMG




Genotype
MGI:7471859
ht2
Allelic
Composition		 Amelxem1(IMPC)Ccpcz/Amelx+
Genetic
Background		 C57BL/6N-Amelxem1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelxem1(IMPC)Ccpcz mutation (1 available); any Amelx mutation (26 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial

growth/size/body
abnormal tooth morphology ( J:211773 )
IMPC - CCP-IMG

hematopoietic system

immune system
enlarged lymph nodes ( J:211773 )
IMPC - CCP-IMG

skeleton




Genotype
MGI:6731244
ot3
Allelic
Composition		 Amelxem1(IMPC)Ccpcz/Y
Genetic
Background		 C57BL/6N-Amelxem1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelxem1(IMPC)Ccpcz mutation (1 available); any Amelx mutation (26 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged heart ( J:211773 )
IMPC - CCP-IMG

craniofacial
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG
absent teeth ( J:211773 )
IMPC - CCP-IMG

digestive/alimentary system
enlarged stomach ( J:211773 )
IMPC - CCP-IMG

endocrine/exocrine glands
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
small seminal vesicle ( J:211773 )
IMPC - CCP-IMG
small testis ( J:211773 )
IMPC - CCP-IMG

growth/size/body
enlarged heart ( J:211773 )
IMPC - CCP-IMG
abnormal tooth morphology ( J:211773 )
IMPC - CCP-IMG
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG
absent teeth ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
small spleen ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
small spleen ( J:211773 )
IMPC - CCP-IMG

integument

reproductive system
small seminal vesicle ( J:211773 )
IMPC - CCP-IMG
small testis ( J:211773 )
IMPC - CCP-IMG

skeleton
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG
absent teeth ( J:211773 )
IMPC - CCP-IMG




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory