All Phenotypes Thyn1<tm1.2Osb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Thyn1^tm1.2Osb
targeted mutation 1.2, Research Institute for Microbial Diseases, Osaka University
MGI:6343245

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Thyn1^tm1.2Osb/Thyn1^tm1.2Osb	involves: C57BL * C57BL/6NSlc * C57BL/6NTac * DBA	MGI:6358111

Allelic Composition	Thyn1^tm1.2Osb/Thyn1^tm1.2Osb
Genetic Background	involves: C57BL * C57BL/6NSlc * C57BL/6NTac * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thyn1^tm1.2Osb mutation (0 available); any Thyn1 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:277335 )

• homozygotes are born in the expected Mendelian ratios and viable and show normal B cell numbers in spleen and inguinal lymph nodes as well as normal percentages of subclasses of B cell lineages in spleen, suggesting normal B cell development

• expression of Pax5 in mature B cells is similar to that in heterozygous and wild-type controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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