Phenotypes associated with this allele

• Allele Symbol: Gm26878^em1Psta
• Allele Name: endonuclease-mediated mutation 1, Pawel Stankiewicz
• Allele ID: MGI:6343542
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gm26878^em1Psta/Gm26878^em1Psta	C57BL/6J-Gm26878^em1Psta	MGI:6781606

Genotype
MGI:6781606

hm1

• Allelic Composition: Gm26878^em1Psta/Gm26878^em1Psta
• Genetic Background: C57BL/6J-Gm26878^em1Psta

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:250380 )

• although homozygotes are born at the expected Mendelian frequency, a small number die within the first few days of birth; in most cases, lethality occurs within the first day of life

respiratory system

respiratory system phenotype ( J:250380 )

N • lungs appear normal with no signs of hyperplasia or hemorrhaging

N • no changes in Foxf1 expression are observed in the lungs at E18.5