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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Utp25em1Glo
endonuclease-mediated mutation 1, Guillermina Lozano
MGI:6355374
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Utp25em1Glo/Utp25em1Glo C57BL/6-Utp25em1Glo MGI:6358144
cx2
 		Trp53tm1Tyj/Trp53tm1Tyj
Utp25em1Glo/Utp25em1Glo 		involves: 129S2/SvPas * C57BL/6 MGI:6358195
cx3
 		Trp53tm1Tyj/Trp53+
Utp25em1Glo/Utp25em1Glo 		involves: 129S2/SvPas * C57BL/6 MGI:6358197


Genotype
MGI:6358144
hm1
Allelic
Composition		 Utp25em1Glo/Utp25em1Glo
Genetic
Background		 C57BL/6-Utp25em1Glo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Utp25em1Glo mutation (0 available); any Utp25 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:272648 )
• no homozygous KO embryos found at ages E7.5, E9.5, E14.5 and no mice at age P21
• empty decidua found at ages E7.5 and E9.5




Genotype
MGI:6358195
cx2
Allelic
Composition		 Trp53tm1Tyj/Trp53tm1Tyj
Utp25em1Glo/Utp25em1Glo
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (240 available)
Utp25em1Glo mutation (0 available); any Utp25 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:272648 )
• no embryos found at ages E7.5, E9.5, E17.5 and no mice at age P21
• empty decidua found at ages E7.5 and E9.5




Genotype
MGI:6358197
cx3
Allelic
Composition		 Trp53tm1Tyj/Trp53+
Utp25em1Glo/Utp25em1Glo
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (240 available)
Utp25em1Glo mutation (0 available); any Utp25 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:272648 )
• no embryos found at ages E7.5, E9.5, E17.5 and no mice at age P21
• empty decidua found at ages E7.5 and E9.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory