All Phenotypes Sec31a<em3(IMPC)H> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sec31a^em3(IMPC)H
endonuclease-mediated mutation 3, Harwell
MGI:6355926

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sec31a^em3(IMPC)H/Sec31a^em3(IMPC)H	C57BL/6N-Sec31a^em3(IMPC)H/H	MGI:6493083
ht2	Sec31a^em3(IMPC)H/Sec31a⁺	C57BL/6N-Sec31a^em3(IMPC)H/H	MGI:6461639

Allelic Composition	Sec31a^em3(IMPC)H/Sec31a^em3(IMPC)H
Genetic Background	C57BL/6N-Sec31a^em3(IMPC)H/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sec31a^em3(IMPC)H mutation (1 available); any Sec31a mutation (70 available)

Data Sources

IMPC Data for Sec31a

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Sec31a^em3(IMPC)H/Sec31a⁺
Genetic Background	C57BL/6N-Sec31a^em3(IMPC)H/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sec31a^em3(IMPC)H mutation (1 available); any Sec31a mutation (70 available)

Data Sources

IMPC Data for Sec31a

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

IMPC - HAR

abnormal locomotor behavior ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased fasting circulating glucose level ( J:211773 )

IMPC - HAR

increased circulating alanine transaminase level ( J:211773 )

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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