Phenotypes associated with this allele

• Allele Symbol: Chd9^em2Ibbr
• Allele Name: endonuclease-mediated mutation 2, Fugaku Aoki
• Allele ID: MGI:6356369
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chd9^em2Ibbr/Chd9^em2Ibbr	C57BL/6N-Chd9^em2Ibbr	MGI:6361091

Genotype
MGI:6361091

hm1

• Allelic Composition: Chd9^em2Ibbr/Chd9^em2Ibbr
• Genetic Background: C57BL/6N-Chd9^em2Ibbr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:270181 )

♀N • female homozygotes are fertile; when mated with male heterozygotes, females produce healthy pups with an average litter size of 6.2

abnormal oocyte morphology ( J:270181 )

♀ • fluorescence recovery after photobleaching (FRAP) analysis using enhanced green fluorescent protein-tagged histone H2B (eGFP-H2B) revealed that mutant growing oocytes exhibit a lower recovery rate and a significantly lower mobile fraction (MF, an index of histone mobility) than wild-type oocytes, indicating a less loosened chromatin structure

cellular

abnormal oocyte morphology ( J:270181 )

♀ • fluorescence recovery after photobleaching (FRAP) analysis using enhanced green fluorescent protein-tagged histone H2B (eGFP-H2B) revealed that mutant growing oocytes exhibit a lower recovery rate and a significantly lower mobile fraction (MF, an index of histone mobility) than wild-type oocytes, indicating a less loosened chromatin structure