Phenotypes associated with this allele

• Allele Symbol: Or2y1g^tm1.1Itl
• Allele Name: targeted mutation 1.1, Ingenious Targeting Labortory
• Allele ID: MGI:6356784
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Or2y1g^tm1.1Itl/Or2y1g^tm1.1Itl	involves: 129S6/SvEvTac * C57BL/6NTac	MGI:6356785

Genotype
MGI:6356785

hm1

• Allelic Composition: Or2y1g^tm1.1Itl/Or2y1g^tm1.1Itl
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

improved glucose tolerance ( J:278264 )

• in s glucose tolerance test, the peak blood glucose level in homozygous mice was significantly lower, and returned to baseline earlier than controls

increased urine glucose level ( J:278264 )

• urinary glucose-creatinine levels were significantly elevated in homozygous mice despite no differences in blood glucose levels compared to controls

• homozygous mice did not have elevated protein/creatinine ratios, suggesting a specific deficit in glucose handling in the renal proximal tubules

renal/urinary system

increased urine glucose level ( J:278264 )

• urinary glucose-creatinine levels were significantly elevated in homozygous mice despite no differences in blood glucose levels compared to controls

• homozygous mice did not have elevated protein/creatinine ratios, suggesting a specific deficit in glucose handling in the renal proximal tubules