Phenotypes associated with this allele

• Allele Symbol: Arhgap36^em1Seul
• Allele Name: endonuclease-mediated mutation 1, Seunghee Lee
• Allele ID: MGI:6357898
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgap36^em1Seul/Arhgap36^em1Seul	Not Specified	MGI:6357924
ot2	Arhgap36^em1Seul/Y	Not Specified	MGI:6357922

Genotype
MGI:6357924

hm1

• Allelic Composition: Arhgap36^em1Seul/Arhgap36^em1Seul
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:277700 )

♀N • normal V2 interneurons (V2-INs), medial motor column (MMC) and hypaxial motor column (HMC) development at age E13.5

♀N • normal motor neuron development between embryonic stages E9.5 and E11.5

♀N • normal spinal cord motor neuron numbers at age E12.5

abnormal spinal cord lateral motor column morphology ( J:277700 )

♀ • increase in LMCm (medial) neurons at age E12.5

♀ • decrease in LMCm (medial) neurons at age E13.5

♀ • decrease in LMCl (lateral) neurons at age E12.5 and E13.5

Genotype
MGI:6357922

ot2

• Allelic Composition: Arhgap36^em1Seul/Y
• Genetic Background: Not Specified

nervous system

nervous system phenotype ( J:277700 )

♂N • normal lateral motor column (LMC) development in late embryonic stage