Phenotypes associated with this allele

• Allele Symbol: Syne2^cpfl8-2J
• Allele Name: cone photoreceptor function loss 8, 2 Jackson
• Allele ID: MGI:6358246
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Syne2^cpfl8-2J/Syne2^cpfl8-2J	B6;129-Syne2^cpfl8-2J/Boc	MGI:6358250

Genotype
MGI:6358250

hm1

• Allelic Composition: Syne2^cpfl8-2J/Syne2^cpfl8-2J
• Genetic Background: B6;129-Syne2^cpfl8-2J/Boc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal ocular fundus morphology ( J:278495 )

• at 3 weeks of age the fundus shows areas of hypo- and hyper-pigmentation and attenuated vessels

abnormal retina blood vessel morphology ( J:278495 )

thin retina outer nuclear layer ( J:278495 )

• slight reduction in thickness at 3 months of age

abnormal retina photoreceptor layer morphology ( J:278495 )

• rod photoreceptors are mislocated in the inner nuclear layer at 3 months of age

decreased total retina thickness ( J:278495 )

• at 3 weeks of age by optical coherence tomography

abnormal cone electrophysiology ( J:278495 )

• diminished cone b-wave ERG response at 3 weeks of age

cardiovascular system

abnormal retina blood vessel morphology ( J:278495 )