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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bcl2l11em1Flv
endonuclease-mediated mutation 1, Richard A Flavell
MGI:6358427
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Bcl2l11em1Flv/Bcl2l11+
Morrbid+/Morrbidem1Flv 		C57BL/6N-Bcl2l11em1Flv +/+ Morrbidem1Flv MGI:6358499
cx2
 		Bcl2l11em1Flv/Bcl2l11+
Morrbidem1Flv/Morrbid+ 		C57BL/6N-Bcl2l11em1Flv Morrbidem1Flv /+ + MGI:6358501


Genotype
MGI:6358499
cx1
Allelic
Composition		 Bcl2l11em1Flv/Bcl2l11+
Morrbid+/Morrbidem1Flv
Genetic
Background		 C57BL/6N-Bcl2l11em1Flv +/+ Morrbidem1Flv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2l11em1Flv mutation (0 available); any Bcl2l11 mutation (36 available)
Morrbidem1Flv mutation (0 available); any Morrbid mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased eosinophil cell number ( J:236609 )
• in the blood and spleen
decreased neutrophil cell number ( J:236609 )
• in the blood and spleen
decreased Ly6C high monocyte number ( J:236609 )
• in the blood and spleen

hematopoietic system
decreased eosinophil cell number ( J:236609 )
• in the blood and spleen
decreased neutrophil cell number ( J:236609 )
• in the blood and spleen
decreased Ly6C high monocyte number ( J:236609 )
• in the blood and spleen




Genotype
MGI:6358501
cx2
Allelic
Composition		 Bcl2l11em1Flv/Bcl2l11+
Morrbidem1Flv/Morrbid+
Genetic
Background		 C57BL/6N-Bcl2l11em1Flv Morrbidem1Flv /+ +
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2l11em1Flv mutation (0 available); any Bcl2l11 mutation (36 available)
Morrbidem1Flv mutation (0 available); any Morrbid mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:236609 )
N
• short-lived myeloid cell (eosinophils, neutrophils and monocytes) numbers are normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory