Phenotypes associated with this allele

• Allele Symbol: Eftud2^em1Lajm
• Allele Name: endonuclease-mediated mutation 1, Loydie Anne Jerome-Majewska
• Allele ID: MGI:6358537
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eftud2^em1Lajm/Eftud2^em1Lajm	C57BL/6-Eftud2^em1Lajm	MGI:6358549
ht2	Eftud2^em1Lajm/Eftud2^+	involves: C57BL/6	MGI:6358542

Genotype
MGI:6358549

hm1

• Allelic Composition: Eftud2^em1Lajm/Eftud2^em1Lajm
• Genetic Background: C57BL/6-Eftud2^em1Lajm

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality at implantation, complete penetrance ( J:278323 )

• embryos are not found post-implantation but are present at the expected frequency at E3.5

Genotype
MGI:6358542

ht2

• Allelic Composition: Eftud2^em1Lajm/Eftud2⁺
• Genetic Background: involves: C57BL/6

mortality/aging

neonatal lethality, incomplete penetrance ( J:278323 )

• the number of heterozygous pups present at weaning is fewer than expected, however normal numbers are seen before birth and at P0 indicating that some mice die shortly after birth

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	mandibulofacial dysostosis, Guion-Almeida type	DOID:0080196	OMIM:610536	J:278323