Phenotypes associated with this allele

• Allele Symbol: Efr3a^tm1Bgsn
• Allele Name: targeted mutation 1, Binggui Sun
• Allele ID: MGI:6358560
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Efr3a^tm1Bgsn/Efr3a^tm1Bgsn Tg(Nes-cre)1Kln/0	involves: 129 * C57BL/6J * SJL	MGI:6358565

Genotype
MGI:6358565

cn1

• Allelic Composition: Efr3a^tm1Bgsn/Efr3a^tm1Bgsn; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129 * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:273433 )

N • adult-born neurons exhibit normal dendritic length, branch numbers and spine density

N • mice exhibit normal hippocampal neural stem cell/neural progenitor cell proliferation and differentiation

decreased neuron apoptosis ( J:273433 )

• in the dentate gyrus of the hippocampus

• however, autophagy is normal

premature neuronal precursor differentiation ( J:273433 )

• increased adult hippocampal neurogenesis in dentate gyrus of 10 week old mice due to differentiation of progenitor cells

cellular

decreased neuron apoptosis ( J:273433 )

• in the dentate gyrus of the hippocampus

• however, autophagy is normal

premature neuronal precursor differentiation ( J:273433 )

• increased adult hippocampal neurogenesis in dentate gyrus of 10 week old mice due to differentiation of progenitor cells