Phenotypes associated with this allele

• Allele Symbol: Psd2^em1Sakag
• Allele Name: endonuclease-mediated mutation 1, Hiroyuki Sakagami
• Allele ID: MGI:6358601
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psd2^em1Sakag/Psd2^em1Sakag	C57BL/6J-Psd2^em1Sakag	MGI:6358606

Genotype
MGI:6358606

hm1

• Allelic Composition: Psd2^em1Sakag/Psd2^em1Sakag
• Genetic Background: C57BL/6J-Psd2^em1Sakag

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:275832 )

N • gross cerebellar anatomy is similar to wild-type controls

abnormal asymmetric synapse morphology ( J:275832 )

• decrease in the density of asymmetric synapses in the middle molecular layer

• however, width of spine heads and the length of the postsynaptic density on asymmetric synapses of Purkinje cells are similar to wild-type controls

behavior/neurological

behavior/neurological phenotype ( J:275832 )

N • do not show any abnormal behavioral neurological signs, such as ataxia

N • no defects in cerebellum-related motor coordination and learning are seen in rotarod or horizontal optokinetic response assays