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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cmtm2aem2Osb
endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI:6359388
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Cmtm2aem2Osb/Cmtm2aem2Osb
Cmtm2bem2Osb/Cmtm2bem2Osb 		involves: C57BL/6NJcl * DBA/2NJcl MGI:6359432


Genotype
MGI:6359432
cx1
Allelic
Composition		 Cmtm2aem2Osb/Cmtm2aem2Osb
Cmtm2bem2Osb/Cmtm2bem2Osb
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cmtm2aem2Osb mutation (2 available); any Cmtm2a mutation (16 available)
Cmtm2bem2Osb mutation (1 available); any Cmtm2b mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:266476 )
N
• mice exhibit normal testicular histology
reduced male fertility ( J:266476 )
• however, spermatozoa are capable of fertilizing eggs in vitro
impaired binding of sperm to zona pellucida ( J:266476 )
• impaired ZP-binding ability




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory