About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cmtm2bem2Osb
endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI:6359391
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Cmtm2aem2Osb/Cmtm2aem2Osb
Cmtm2bem2Osb/Cmtm2bem2Osb 		involves: C57BL/6NJcl * DBA/2NJcl MGI:6359432


Genotype
MGI:6359432
cx1
Allelic
Composition		 Cmtm2aem2Osb/Cmtm2aem2Osb
Cmtm2bem2Osb/Cmtm2bem2Osb
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cmtm2aem2Osb mutation (2 available); any Cmtm2a mutation (16 available)
Cmtm2bem2Osb mutation (1 available); any Cmtm2b mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:266476 )
N
• mice exhibit normal testicular histology
reduced male fertility ( J:266476 )
• however, spermatozoa are capable of fertilizing eggs in vitro
impaired binding of sperm to zona pellucida ( J:266476 )
• impaired ZP-binding ability




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory