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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Abtb2tm1Zgwg
targeted mutation 1, Zhugang Wang
MGI:6359867
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Abtb2tm1Zgwg/Abtb2tm1Zgwg involves: 129/Sv * C57BL/6 MGI:6393995


Genotype
MGI:6393995
hm1
Allelic
Composition
Abtb2tm1Zgwg/Abtb2tm1Zgwg
Genetic
Background
involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abtb2tm1Zgwg mutation (0 available); any Abtb2 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system
• reduced recruitment of activated hepatic stem cells to injured areas in response to carbon tetrachloride (CCl4)-induced chronic liver damage (J:278621)
• in response to carbon tetrachloride (CCl4)-induced acute liver damage, as measured by BrdU incorporation (J:280009)

mortality/aging
• less fibrosis in response to carbon tetrachloride (CCl4)-induced chronic liver damage (J:278621)
• delayed response to carbon tetrachloride (CCl4)-induced acute liver damage, as measured by serum alanine transferase (ALT) levels (J:280009)





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory