Phenotypes associated with this allele

• Allele Symbol: Cmklr2^tm1.1Dgen
• Allele Name: targeted mutation 1.1, Deltagen
• Allele ID: MGI:6360463
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cmklr2^tm1.1Dgen/Cmklr2^tm1.1Dgen	involves: C57BL/6J	MGI:6360466

Genotype
MGI:6360466

hm1

• Allelic Composition: Cmklr2^tm1.1Dgen/Cmklr2^tm1.1Dgen
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased brown fat cell size ( J:273922 )

• in the scapular BAT of untreated mice

decreased white fat cell size ( J:273922 )

• in inguinal, mesenteric, and gonadal WAT of untreated mice

• in mesenteric WAT of dehydroepiandrosterone (DHEA)-treated mice

increased white fat cell size ( J:273922 )

• in inguinal and gonadal WAT of dehydroepiandrosterone (DHEA)-treated mice

growth/size/body

increased body weight ( J:273922 )

• in untreated mice

decreased susceptibility to weight gain ( J:273922 )

• in dehydroepiandrosterone (DHEA)-treated mice

homeostasis/metabolism

increased circulating estradiol level ( J:273922 )

• in untreated mice

• to a lesser extent in dehydroepiandrosterone (DHEA)-treated mice

increased circulating LDL cholesterol level ( J:273922 )

• in dehydroepiandrosterone (DHEA)-treated mice