Phenotypes associated with this allele

• Allele Symbol: Slc2a6^em1Rbr
• Allele Name: endonuclease-mediated mutation 1, Robert Brink
• Allele ID: MGI:6360858
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc2a6^em1Rbr/Slc2a6^em1Rbr	C57BL/6J-Slc2a6^em1Rbr	MGI:6360860

Genotype
MGI:6360860

hm1

• Allelic Composition: Slc2a6^em1Rbr/Slc2a6^em1Rbr
• Genetic Background: C57BL/6J-Slc2a6^em1Rbr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:266077 )

♀ • females, but not males, fed a Western diet exhibit decreased adiposity

♀ • however, food intake is not different from wild-type mice and body weight is not altered

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:266077 )

N • whole body glucose tolerance is not affected and mice maintain normal fasting insulin levels when fed a chow or Western diet

decreased respiratory quotient ( J:266077 )

♀ • females fed a chow diet show lower respiratory exchange ratio during the light cycle compared to wild-type mice

♀ • however, females fed a Western diet do not show this change in respiratory exchange ratio and females fed a Western or chow diet show similar oxygen consumption and locomotor activity to wild-type mice