Phenotypes associated with this allele

• Allele Symbol: Scml1^tm1.2Atot
• Allele Name: targeted mutation 1.2, Attila Toth
• Allele ID: MGI:6362616
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scml1^tm1.2Atot/Scml1^tm1.2Atot	STOCK Scml1^tm1.2Atot/Atot	MGI:6362620
ot2	Scml1^tm1.2Atot/Y	STOCK Scml1^tm1.2Atot/Atot	MGI:6362621

Genotype
MGI:6362620

hm1

• Allelic Composition: Scml1^tm1.2Atot/Scml1^tm1.2Atot
• Genetic Background: STOCK Scml1^tm1.2Atot/Atot

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:278848 )

♀ • viable and fertile with no gross abnormalities

Genotype
MGI:6362621

ot2

• Allelic Composition: Scml1^tm1.2Atot/Y
• Genetic Background: STOCK Scml1^tm1.2Atot/Atot

reproductive system

reproductive system phenotype ( J:278848 )

♂N • males are fertile

♂N • no increase in apoptosis is seen in the seminiferous tubules

♂N • no abnormalities in male meiosis, sex body formation or sex chromosome silencing are detected

abnormal spermatocyte morphology ( J:278848 )

♂ • only a small minority of pachytene spermatocytes contain dense bodies unlike in controls and when present the dense bodies are never or rarely localized in or near sex bodies, respectively

cellular

abnormal spermatocyte morphology ( J:278848 )

♂ • only a small minority of pachytene spermatocytes contain dense bodies unlike in controls and when present the dense bodies are never or rarely localized in or near sex bodies, respectively