cardiovascular system
• increased cardiomyocyte cross-sectional area more so than in wild-type mice in response to pressure overload
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• more so than in wild-type mice in response to pressure overload
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• more so than in wild-type mice in response to pressure overload
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• however, the phenotype is improved when mice are treated with N-acetyl-L-cysteine
• more so than in wild-type mice in response to pressure overload
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• increased cardia hypertrophy (with increased heart weight and increased cardiomyocyte cross-sectional area), cardiac fibrosis and increased lung weight more so than in wild-type mice in response to pressure overload
• however, the phenotypes are improved when mice are treated with N-acetyl-L-cysteine
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cellular
• exacerbated reduction complex I, II and IV activity in response to pressure overload
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respiratory system
• more so than in wild-type mice in response to pressure overload
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homeostasis/metabolism
• increased cardia hypertrophy (with increased heart weight and increased cardiomyocyte cross-sectional area), cardiac fibrosis and increased lung weight more so than in wild-type mice in response to pressure overload
• however, the phenotypes are improved when mice are treated with N-acetyl-L-cysteine
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muscle
• increased cardiomyocyte cross-sectional area more so than in wild-type mice in response to pressure overload
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• more so than in wild-type mice in response to pressure overload
• however, the phenotype is improved when mice are treated with N-acetyl-L-cysteine
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growth/size/body
• more so than in wild-type mice in response to pressure overload
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• more so than in wild-type mice in response to pressure overload
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