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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Loxem1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6362805
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Loxem1(IMPC)Mbp/Loxem1(IMPC)Mbp C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd MGI:6480495
ht2
 		Loxem1(IMPC)Mbp/Lox+ C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd MGI:6492932


Genotype
MGI:6480495
hm1
Allelic
Composition		 Loxem1(IMPC)Mbp/Loxem1(IMPC)Mbp
Genetic
Background		 C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Loxem1(IMPC)Mbp mutation (1 available); any Lox mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial

homeostasis/metabolism
edema ( J:211773 )
IMPC - UCD

mortality/aging




Genotype
MGI:6492932
ht2
Allelic
Composition		 Loxem1(IMPC)Mbp/Lox+
Genetic
Background		 C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Loxem1(IMPC)Mbp mutation (1 available); any Lox mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo

growth/size/body
enlarged spleen ( J:211773 )
IMPC - UCD

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - UCD

immune system
enlarged spleen ( J:211773 )
IMPC - UCD

integument

limbs/digits/tail

renal/urinary system
small kidney ( J:211773 )
IMPC - UCD

skeleton




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory