Phenotypes associated with this allele

• Allele Symbol: Gne^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6363412
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gne^em1(IMPC)Mbp/Gne^em1(IMPC)Mbp	C57BL/6N-Gne^em1(IMPC)Mbp/MbpMmucd	MGI:6492867
ht2	Gne^em1(IMPC)Mbp/Gne^+	C57BL/6N-Gne^em1(IMPC)Mbp/MbpMmucd	MGI:6731338

Genotype
MGI:6492867

hm1

• Allelic Composition: Gne^em1(IMPC)Mbp/Gne^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Gne^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Gne

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - UCD

embryo

abnormal neural tube morphology ( J:211773 )

♂

IMPC - UCD

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:6731338

ht2

• Allelic Composition: Gne^em1(IMPC)Mbp/Gne⁺
• Genetic Background: C57BL/6N-Gne^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Gne

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - UCD

vision/eye

cataract ( J:211773 )

♀

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

♀

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - UCD