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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aars2tm2.1Htyy
targeted mutation 2.1, Henna Tyynismaa
MGI:6368037
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aars2tm2.1Htyy/Aars2tm2.1Htyy involves: 129S6/SvEvTac * C57BL/6JOlaHsd * C57BL/6NCrl MGI:6368041
ht2
 		Aars2tm2.1Htyy/Aars2+ involves: 129S6/SvEvTac * C57BL/6JOlaHsd * C57BL/6NCrl MGI:6368042


Genotype
MGI:6368041
hm1
Allelic
Composition		 Aars2tm2.1Htyy/Aars2tm2.1Htyy
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6JOlaHsd * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aars2tm2.1Htyy mutation (0 available); any Aars2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:257856 )
• no homozygous mice are obtained, however time of lethality is not specified except that small embryos are seen at E8.5

growth/size/body
decreased embryo size ( J:257856 )
• embryos are smaller at E8.5

embryo
decreased embryo size ( J:257856 )
• embryos are smaller at E8.5




Genotype
MGI:6368042
ht2
Allelic
Composition		 Aars2tm2.1Htyy/Aars2+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6JOlaHsd * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aars2tm2.1Htyy mutation (0 available); any Aars2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:257856 )
• mice show no differences in weight gain, behavior, cerebellum morphology, neuronal loss, or heart weight during the first year of life




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory