Phenotypes associated with this allele

• Allele Symbol: Tg(CAG-Tmem135)#Aike
• Allele Name: transgene insertion, Akihiro Ikeda
• Allele ID: MGI:6368630
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CAG-Tmem135)#Aike/0	involves: C57BL/6J * FVB/NJ	MGI:6368812

Genotype
MGI:6368812

tg1

• Allelic Composition: Tg(CAG-Tmem135)#Aike/0
• Genetic Background: involves: C57BL/6J * FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal mitochondrial morphology ( J:237184 )

• over-fragmented mitochondrial networks in mouse embryonic fibroblasts

decreased mitochondrial size ( J:237184 )

• in mouse embryonic fibroblasts

abnormal mitochondrial physiology ( J:237184 )

• reduced basal oxygen consumption rate and ATP production in mouse embryonic fibroblasts

• however, maximal respiration and spare respiration capacity are normal

increased mitochondrial fission ( J:237184 )

• in mouse embryonic fibroblasts

oxidative stress ( J:237184 )

• in mouse embryonic fibroblasts