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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dcaf6tm1.1Ntuy
targeted mutation 1.1, National Taiwan University
MGI:6368839
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dcaf6tm1.1Ntuy/Dcaf6tm1.1Ntuy B6JNarl.Cg-Dcaf6tm1.1Ntuy MGI:6368847


Genotype
MGI:6368847
hm1
Allelic
Composition
Dcaf6tm1.1Ntuy/Dcaf6tm1.1Ntuy
Genetic
Background
B6JNarl.Cg-Dcaf6tm1.1Ntuy
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dcaf6tm1.1Ntuy mutation (0 available); any Dcaf6 mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• reduced muscle force generation
• delayed skeletal muscle regeneration following cardiotoxin injection
• impaired skeletal muscle differentiation and myotube formation during regeneration

behavior/neurological
• reduced latency to fall on a rotarod
• reduced muscle force generation
• impaired adaptive exercise performance in a forced treadmill test

homeostasis/metabolism
• reduced muscle force generation
• impaired adaptive exercise performance in a forced treadmill test





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory