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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tppp2em1Nju
endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
MGI:6368880
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tppp2em1Nju/Tppp2em1Nju Not Specified MGI:6368882


Genotype
MGI:6368882
hm1
Allelic
Composition		 Tppp2em1Nju/Tppp2em1Nju
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tppp2em1Nju mutation (0 available); any Tppp2 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
decreased litter size ( J:279929 )
• from male mice

cellular
abnormal mitochondrial morphology ( J:279929 )
• sperm mitochondria are irregular and lack inner mitochondrial membrane
abnormal mitochondrial ATP synthesis coupled electron transport ( J:279929 )
• impaired in sperm with reduced ATP content




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory