All Phenotypes Slc12a8<em1Imai> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc12a8^em1Imai
endonuclease-mediated mutation 1, Shin-ichiro Imai
MGI:6370147

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc12a8^em1Imai/Slc12a8^em1Imai	B6.Cg-Slc12a8^em1Imai	MGI:6370154

Allelic Composition	Slc12a8^em1Imai/Slc12a8^em1Imai
Genetic Background	B6.Cg-Slc12a8^em1Imai

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a8^em1Imai mutation (0 available); any Slc12a8 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:280135 )

• fewer than expected mice were born

homeostasis/metabolism

abnormal nucleotide metabolism ( J:280135 )

• decreased NAD+ levels in the jejunum and ileum associated with nicotinamide mononucleotide transport

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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